个人简历:
2006年北京大学,应用数学学士
2011年北京大学,统计学博士
2012年耶鲁大学公共卫生学院,博士后
2012年-2015年耶鲁大学公共卫生学院,副研究员
2015年至今清华大学统计学研究中心,研究员
主要科研领域及方向:
统计学以及统计学在生物大数据和精准医学中的应用,包括统计遗传学、全基因组关联分析、下一代测序数据的建模和分析、癌症基因组学、大规模生物相互作用网络和多组学数据整合等。
代表论文:
1.Hou L, Sun N, Mane S, Sayward F, et al. (2017) Impact of genotyping errors onstatistical power of association tests in genomic analyses: A case study. Genetic Epidemiology, 41:152-162
2. Foxman E, Storer J, Fitzgerald M, Wasik B, Hou L, Zhao H, Turner P, Pyle A and Iwasaki A. (2015) Temperature-dependent innate defense against the common coldvirus limits viral replication at warm temperature in mouse airway cells. Proceedingsof the National Academy of Sciences, 112(3):827-32.
3.Evans B, Gloria-Soria A, Hou L, McBride C, Bonizzoni M, Zhao H and Powell J. (2015) A multipurpose high throughput SNP chip for the Dengue and Yellow Fevermosquito, Aedesaegypti. G3 (Bethesda), 5:711-718.
4.Hou L, Chen M, Zhang K, Cho J and Zhao H. (2014) Guilt by rewiring: geneprioritization through network rewiring in Genome Wide Association Studies. Human Molecular Genetics, 23:2780-2790.
5.Hou L, Ma T and Zhao H. (2014) Incorporating functional annotation information inprioritizing disease associated SNPs from genome wide association studies. SCIENCECHINA Life Sciences, 57:1072-1079.
6.Hou Land Zhao H. (2013) A review of post-GWAS prioritization approaches. Frontiers in Genetics, 4:280.
7.Hou L, Wang L, Qian M, Li D, Tang C, Zhu Y, Deng M and Li F. (2011) Modularanalysis of the probabilistic genetic interaction network. Bioinformatics, 27:853-859.
8.Cai X#, Hou L#, Su N#, Hu H, Deng M and Li X. (2010) Systematic identificaiton ofconserved motif modules in the human genome. BMC Genomics, 11:567. (co-firstauthor)
联系方式:
北京市清华大学统计学研究中心
邮政编码:100084
联系电话:010-62789162
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