谢道昕

谢道昕
谢道昕 博士生导师 教授

教育部长江学者特聘教授

国家杰出青年基金获得者

 

个人简历:

2006-现在:清华大学(《百人计划》责任教授)
2002-2006:新加坡分子细胞生物所(实验室主任,资深科学家)
1999-2002:新加坡国立大学农业分子生物所(实验室主任,助理教授)
1994-1999:英国EastAnglia大学(Senior Research Associate)
1990-1994:英国John Innes研究中心和英国Leicester大学(Research Associate)
1984-1990:中国农科院研究生院(Ph.D.,MSc.)
1983-1984:湖南棉花科学研究所(Research Assistant)
1979-1983:湖南农学院(BSc.)

主要科研领域及方向:

      生物体蛋白质的 “ 转录 / 翻译 ” 与 “ 降解 ” 是同样重要的命题。人们在 “ 转录和翻译 ” 的研究中取得了众所周知的突破。可以预见, 对蛋白质是如何被特一性降解的研究, 必将对生命科学的发展产生重要影响。
该实验室主要采用植物分子遗传、生物化学、功能基因组和蛋白组学等方法 , 研究蛋白降解途径和植物激素茉莉素调控植物生长发育及抗性的机理。

代表论文:

1.        Qi, T., Huang, H., Wu, D., Yan J., Qi Y., Song, S., and Xie, D. (2014). Arabidopsis DELLA and JAZ Proteins Bind the WD-repeat/bHLH/MYB Complex to Modulate Gibberellin and Jasmonate Signaling Synergy. Plant Cell: in press

2.        Song, S., Huang, H., Gao, H., Wang, J., Wu, D., Liu, X., Yang, S., Zhai, Q., Li, C., Qi, T., and Xie, D. (2014) Interaction of MYC2 with EIN3 Modulates Antagonism between Jasmonate and Ethylene Signaling. Plant Cell doi:10.1105/tpc.113.120394

3.        Hu P, W Zhou, Z Cheng, M Fan, L Wang, Xie D. (2013) JAV1 controls Jasmonate-regulated plant defense. Molecular Cell  50:5014-15

4.        Yan J, Li H, Li S, Yao R, Deng H, Xie Q, Xie D. (2013) The Arabidopsis F-box protein CORONATINE INSENSITIVE 1 is stabilized by SCFCOI1 and degraded via the 26S proteasome pathway. Plant Cell 25: 486-498

5.        Song S, T Qi, M Fan, X Zhang, H Gao, H Huang, D Wu, H Guo, Xie D. (2013) The bHLH Subgroup IIId Factors Negatively Regulate Jasmonate-mediated Plant Defense and Development.PLoS Genetics 9, e1003653

6.        Shan X., Yan J., Xie D. (2012) Comparison of phytohormone signaling mechanisms.Current Opinion in Plant Biology 15:84-91. 2012

7.        Qi T, S Song, Q Ren, D Wu, H Huang, Y Chen, M Fan, J Xie, W Peng, C Ren, D Xie. (2011) The Jasmonate-ZIM-domain Proteins Interact with the WD-repeat/bHLH/MYB Complexes to Control Jasmonate-regulated Anthocyanin Accumulation and Trichome Initiation in Arabidopsis. Plant Cell 23:1795-1814

8.        Song S, Qi T, Huang H, Ren Q, Wu D, Chang C, Peng W, Liu Y, Peng Y, Xie D. (2011) The Jasmonate-ZIM-domain Proteins Interact with the R2R3-MYB Transcription Factors MYB21 and MYB24 to Control Jasmonate-regulated Stamen Development in Arabidopsis. Plant Cell23:1000-13.

9.        Yan,J., Zhang,C., Gu,M., Bai,Z, Zhang,W., Qi,T, Cheng,Z., Peng,W, Luo,H., Nan,F., Wang,Z., Xie,D. (2009) The Arabidopsis CORONATINE INSENSITIVE 1 protein is a jasmonate receptor. Plant Cell 21: 2220–36.

10.    Cheng,H., Song,S., Xiao,L., Soo,H., Cheng,Z., Xie,D*,Peng,J  (2009) Gibberellin Acts Through Jasmonate to Control the Expression of MYB21, MYB24 and MYB57 to Promote Stamen Filament Growth in Arabidopsis. PLoS Genetics 5(3):e1000440 (*co-senior author)

11.    Tan,L., Li,X., Liu,F., Sun,X., Li,C., Zhu,Z., Fu,Y., Cai,H., Wang,X., Xie,D*,Sun.C. (2008) Control of a key transition from prostrate to erect growth in rice domestication. Nature Genetics40:1360-4 (*co-senior author).

12.    Xiao,S., Dai,L., Liu,L., Wang,Z., Peng,W., Xie,D. (2004) COS1: an Arabidopsis coi1 suppressor essential forregulation of jasmonate-mediated plant defense and senescence. Plant Cell 16: 1132-42.

13.    Liu,F., Ni,W., Griffith,M.E., Huang,Z., Chang,C., Peng,W., Ma,H. and Xie, D. (2004) The ASK1 and ASK2 Genes Are Essential for Arabidopsis Early Development. Plant Cell 16:5-20.

14.    Xu,L., Liu,F., Lechner,E., Genschik,P., Crosby,W.L., Ma,H., Peng,W., Huang,D., andXie,D. (2002) The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis. Plant Cell 14:1919-35.

15.   Xie,D., Feys,B.F., James,S., Nieto-Rostro,M. and Turner,J.G. (1998) COI1: an Arabidopsis gene required for jasmonate-regulated defense and fertility. Science 280:1091-94.

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