刘晓

刘晓
刘晓 博士生导师 研究员

 “青年千人计划”获得者

 

 

个人简历:       

1994       南京大学生物系   学士
1997       北京大学细胞遗传系 硕士
2005       约翰霍普金斯医学院生物物理系 博士
2011            斯坦福大学发育生物学系 博士后
2012-至今     清华大学 生命科学学院 PI 

主要科研领域及方向:

        实验室主要通过开发和利用高通量实验技术,从功能基因组学和系统生物学角度,主要以线虫神经系统为模型,研究细胞命运决定和进化的分子机制 。

代表论文:   

  • Liu, X., Long, F., Peng, H., Aerni, S.J., Jiang, M., Sánchez-Blanco A., Murray. J.I., Preston, E., Mericle, B., Batzoglou, S., Myers, G., and Kim, S.K. (2009). Analysis of cell fate from single-cell gene expression profiles in C. elegans. Cell 139: 623 - 633
  • Long, F., Peng, H., Liu, X., Kim, S.K., and Myers, G. (2009). A 3D digital atlas of C. elegansand its applicationto single-cell analyses. Nature Mathods 6: 667 - 672
  • Long, F., Peng, H., Liu, X., Kim, S.K., and Myers, G. (2008). Automatic Recognition of Cells (ARC) for 3D images of C. elegans. Recomb.
  • Peng, H., Long, F., Liu, X., Kim, S.K., and Myers, E.W. (2008). Straightening Caenorhabditis elegans images. Bioinformatics 24, 234-242
  • Liu, X., C.K. Lee, N.D. Clarke, and J.D. Lieb (2006) Quantification of chromatin contributions to DNA-binding site utilization. Genome Res. 16: 1517 – 1528
  • Liu, X., Noll, D.M., Lieb, J.D., and Clarke, N.D. (2005) DIP-chip: Rapid and accurate determination of DNA-binding specificity. Genome Res. 15: 421 – 427
  • Liu, X. and Clarke, N. D. (2002) Rationalization of gene regulation by a eukaryotic transcription factor: calculation of regulatory region occupancy from predicted binding affinities. J. Mol. Biol.323:1-8.
  • Linask, K.K., Ludwig, C., Han, M., Liu, X., Radice, G.L. & Knudsen K.A. (1998) N-Cadherin/Catenin Mediated Morphoregulation of Somite formation. Developmental Biology202, 85-102.
  • He, W., Gao, J., Liu, X., & Sun, F. (1996) Establishment of Embryonic  Stem Cell Lines Derived from Outbred Mouse Embryos and Production of Chimeras. Chinese Journal of Developmental & Reproductive Biology 5, 21-24.

 

联系方式: 

清华大学生命科学学院,生物技术馆4-213
北京100084,中国
电话: (010)6279-2304
E-mail: 该Email地址已收到反垃圾邮件插件保护。要显示它您需要在浏览器中启用JavaScript。